Cerebral glucose metabolism abnormalities in patients with major depressive symptoms in pre‐dialytic chronic kidney disease: Statistical parametric mapping analysis of F‐18‐FDG PET, a preliminary study

Abstract

PDCKD patients with depressive symptoms had decreased cerebral glucose metabolism in several brain areas. For the right orbitofrontal cortex there was a negative correlation with HDRS in PDCKD patients. The present findings provide functional neuroimaging support for abnormal cerebral glucose metabolism in PDCKD patients with depressive symptoms.