Protective effect of annexin‐A1 against irreversible damage to cavernous tissue after cavernous nerve injury in the rat

Abstract

• This is the first report that, by assessing changes in the intracavernous pressure and karyometry, demonstrates the protective effect of annexin-A1 in an animal model of cavernous nerve injury. We found that annexin-A1 effectively preserved erectile function, evidently through significantly protecting the corpus cavernosum tissue against fibrosis.