Validation of variants in<i>SLC28A3</i>and<i>UGT1A6</i>as genetic markers predictive of anthracycline‐induced cardiotoxicity in children

Abstract

. We validated genetic variants in two genes predictive of ACT in an independent cohort. A prediction model combining replicated genetic variants as well as clinical risk factors might be able to identify high- and low-risk patients who could benefit from alternative treatment options.