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Metal Requirements of Alkaline Phosphatases of Human and Rabbit Leukocytes
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1957
Year
Metal RequirementsRedox BiologyCellular PhysiologyOxidative StressInflammationRabbit LeukocyteBiological Inorganic ChemistryCell SignalingBiochemistryPharmacologyCell BiologyAlkaline PhosphatasesNatural SciencesMetalloproteinPhysiologyBioactive MetalCellular BiochemistryHuman LeukocyteMedicine
EDTA inhibits alkaline phosphatase activity of the human leukocyte. The rabbit leukocyte is, however, not so affected. There seem to be 2 alkaline phosphatases in the human leukocytes: one requiring magnesium and the other zinc for its activation.