Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients - Concepedia

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Publication | Open Access

Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients

DOI Full Paper Access

86

Citations

37

References

2011

Year

Yago González‐Lama, Fernando Bermejo, Antonio López–Sanromán, Valle García–Sánchez, María Esteve, José Luis Cabriada, Adrián G. McNicholl, Ramón Pajares, Francesc Casellas, Olga Merino,

Alimentary Pharmacology & Therapeutics

Abstract

Our results do not support determination of TPMT activity or 6TGN concentrations to predict treatment outcome, and no useful serum metabolites threshold value to adjust the drug's dose was identified.

References

	Year	Citations

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