THE PATHOGENESIS OF LUPUS ERYTHEMATOSUS AND ALLIED CONDITIONS

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Article1 January 1948THE PATHOGENESIS OF LUPUS ERYTHEMATOSUS AND ALLIED CONDITIONSPAUL KLEMPERER, M.D.PAUL KLEMPERER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-28-1-1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1872 when Kaposi1published his first report of acute lupus erythematosus, medicine was still dominated by the pathologic-anatomic doctrine that disease is the result of alterations of bodily structure. Today the study of pathogenesis aims at a full comprehension and integration of all the factors of the external and internal environment which bring about that altered state of life, called disease. Inquiry into the genesis of a disease can no longer be content with the mere perception of structural alterations. Yet the definition of most maladies still depends upon an exact knowledge of characteristic organ and tissue changes. 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ROBINSON, M.D., F.A.C.P., EDWARD W. BOLAND, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., WALLACE GRAHAM, M.D., F.R.C.P. (C), L. MAXWELL LOCKIE, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D.Lupus erythematosusNATURAL HISTORY OF LUPUS ERYTHEMATOSUS DISSEMINATUS*RALPH A. JESSAR, M.D., RONALD W. LAMONT-HAVERS, M.D., CHARLES RAGAN, M.D.POLYARTERITIS NODOSA CAUSING DEAFNESS IN AN ADULT: REPORT OF A CASE WITH SPECIAL REFERENCE TO CONCEPTS ABOUT THE DISEASE*NEIL F. MCNEIL, M.D., MEYER BERKE, M.D., I. M. REINGOLD, M.D.SKIN LESIONS OF ACUTE LUPUS ERYTHEMATOSUS AND ACUTE X-RAY DERMATITISINTUSSUSCEPTION DUE TO ECTOPIC PANCREATIC TISSUEAddendumAcute phase reactantsLUPUS ERYTHEMATOSUS DISSEMINATUS (LIBMAN-SACKS' DISEASE)Nature of collagen diseasesPeriarteritis nodosaCollagen Diseases: Pathology And Clinical CourseThe Mucopolysaccharides of the Ground Substance of Connective TissueAcute and Subacute Disseminated Lupus ErythematosusAcute Disseminated Lupus ErythematosusRECURRENT ACUTE LUPUS ERYTHEMATOSUS DISSEMINATUS: REPORT OF A CASE WHICH HAS SURVIVED TWENTY-THREE YEARS AFTER THE ONSET OF SYSTEMIC MANIFESTATIONS*SOLOMON BEN-ASHER, M.D.Fever, skin rash, azotemia and respiratory failure∗∗From the Departments of Internal Medicine and Pathology, Washington University School of Medicine and the Barnes Hospital, St. Louis, Mo.The role of allergy in the pathogenesis of rheumatic fever 1 January 1948Volume 28, Issue 1Page: 1-11KeywordsHospital medicineLupus erythematosusPathogenesisPathology and laboratory medicinePerception ePublished: 1 December 2008 Issue Published: 1 January 1948 Copyright & PermissionsCopyright, 1948, by The American College of PhysiciansPDF downloadLoading ...