EFFECTS OF SUBLINGUAL NITROGLYCERIN ON PULMONARY ARTERIAL PRESSURE IN PATIENTS WITH LEFT VENTRICULAR FAILURE

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Article1 January 1959EFFECTS OF SUBLINGUAL NITROGLYCERIN ON PULMONARY ARTERIAL PRESSURE IN PATIENTS WITH LEFT VENTRICULAR FAILUREJOHN B. JOHNSON, M.D., F.A.C.P., AUDREY FAIRLEY, B.S., CLARENCE CARTER, M.S.JOHN B. JOHNSON, M.D., F.A.C.P., AUDREY FAIRLEY, B.S., CLARENCE CARTER, M.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-1-34 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe retrosternal distress associated with paroxysmal dyspnea may be quite severe, and in many instances it is described by the patient as pain.1 This discomfort is sometimes interpreted by the physician as the pain of angina pectoris, resulting in the administration of nitroglycerin.In a recent publication we reported that frequently the retrosternal discomfort and breathlessness of paroxysmal dyspnea were promptly relieved by the sublingual administration of nitroglycerin. The clinical effectiveness of nitroglycerin over other emergency measures was so unmistakable in many of our patients that we now use the drug routinely, and the patients now insist on having the...Bibliography1. ViarHarrison WNTR: Chest pain in association with pulmonary hypertension: its similarity to pain in coronary disease, Circulation 5: 1-11, 1952. CrossrefMedlineGoogle Scholar2. JohnsonGrossHale JBJFE: Effects of sublingual administration of nitroglycerin on pulmonary-artery pressure in patients with failure of the left ventricle, New England J. Med. 257: 1114-1117, 1957. CrossrefMedlineGoogle Scholar3. HellemsHaynesDexter HKFWL: Pulmonary capillary pressure in man, J. Appl. Physiol. 2: 24, 1949. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.*Presented at the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, April 28, 1958.From the Cardiovascular Laboratory of the Department of Medicine of Freedmen's Hospital and Howard University College of Medicine.†Supported in part by a grant-in-aid from the National Heart Institute.Requests for reprints should be addressed to John B. Johnson, M.D., Department of Medicine, Howard University School of Medicine, Washington 1, D.C. 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