Not a simple fat‐soluble vitamin: changes in serum 25‐(OH)D levels are predicted by adiposity and adipocytokines in older adults

Abstract

Body fat is not simply a passive reservoir for 25-(OH)D. In addition to season and sun exposure, 25-(OH)D levels appear to be determined by metabolic and, to a lesser extent, inflammatory factors, and these appear to mediate the effects of adiposity on change in 25-(OH)D.