THE SITE OF ACTION OF THYROXIN ON WATER‐METABOLISM

Abstract

1. Kidneys originating from thyroxinised dogs, when transplanted simultaneously with control kidneys to a donor anæsthetised with chloralosane, have been found to secrete more rapidly and to give larger responses to saline infusion and to hypophysectomy than the controls. 2. The method adopted and the results obtained demonstrate that the diuretic effect of thyroxin is due, at least in part, to a direct action on the kidney.