Journal of Biological Chemistry · 1982 · 44 citations · 56 references
Life SciencesBiochemistryPhysiologyEnzymologyMetabolic RegulationMetabolismCarbohydrate MetabolismEnzyme KineticsEnzyme RegulationGlycogen MetabolismHormonal Control Of MetabolismMuscle PhysiologyActivity Ratio AnalysisGlucose-6-phosphatase RegulationGlycogen Phosphorylase KinaseGlycogen Synthase Kinase RegulationGlycolysis In Skeletal MuscleMuscle Glycogen MetabolismRegulation Of Enzyme Activity By PhosphorylationSkeletal Muscle Glucose Metabolism
Phosphorylation of rabbit skeletal muscle glycogen synthase in vivo in response to hormones was investigated.Methods were developed to purify the synthase without altering its kinetic parameters, thereby indicating constancy of the synthase phosphorylation state.The enzyme from control rabbits had an activity ratio (-glucose-6-P/+glucose-6-P) of 0.24, K, for glucose-6-
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