Concepedia

Publication | Closed Access

Glucose Sensing O-GlcNAcylation Pathway Regulates the Nuclear Bile Acid Receptor Farnesoid X Receptor (FXR)

DOI

65

Citations

28

References

2013

Year

Wahiba Berrabah, Pierrette Aumercier, Céline Gheeraert, Hélène Dehondt, Emmanuel Bouchaert, Jérémy Alexandre, Maheul Ploton, Claire Mazuy, Sandrine Caron, Anne Tailleux,
Hepatology

Abstract

FXR activity is regulated by glucose fluxes in hepatocytes through a direct posttranslational modification catalyzed by the glucose-sensing hexosamine biosynthetic pathway.

References

YearCitations

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