Mechanistic correlations between two itch biomarkers, cytokine interleukin-31 and neuropeptide β-endorphin, via STAT3/calcium axis in atopic dermatitis - Concepedia

Concepedia

Publication | Open Access

Mechanistic correlations between two itch biomarkers, cytokine interleukin-31 and neuropeptide β-endorphin, via STAT3/calcium axis in atopic dermatitis

DOI Full Paper Access

65

Citations

31

References

2012

Year

Chien‐Hung Lee, Chien‐Hui Hong, Wensi Yu, Hung‐Yi Chuang, S K Huang, G.-S. Chen, Tohru Yoshioka, Masatoshi Sakata, Wei‐Ting Liao, Ying‐Chin Ko,

British Journal of Dermatology

Abstract

IL-31 receptor activation in keratinocytes induces calcium influx and STAT3-dependent production of β-endorphin. These results might contribute to an understanding of the regulatory mechanisms underlying peripheral itch.

References

	Year	Citations

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