OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) · 1978 · 24 citations · 0 references
MedicineRadiation OncologyRadiologyRadiation DosimetryRadiobiologyRadionuclide TherapyBiological Effects Of RadiationBone Marrow PhysiologyBone RegenerationRadiation TherapyRadiobiological ConsiderationsTissue Responses To RadiationBone Marrow RecoveryBone Marrow RegenerationIonizing IrradiationMarrow Radiation ExposureRadiation Effects On The Hematopoietic SystemTime-course EffectsTissue Regeneration After Radiation
Regeneration of bone marrow following radiation only was investigated using /sup 111/In as a bone scanning agent. Factors which influence local marrow regeneration are dose, age of the patient, and the total amount of the marrow which was irradiated. Time effects are not demonstrated in this study, except to the extent that most regeneration did occur within the first 12 months following irradiation. The most striking finding is the effect of the irradiation volume. Apparent inconsistencies in earlier reports concerning the dose effect could be explained by this effect alone.