The role of urinary soluble endoglin in the diagnosis of pre‐eclampsia: comparison with soluble fms‐like tyrosine kinase 1 to placental growth factor ratio

Abstract

We have provided evidence that soluble endoglin is present and elevated in the urine of women who develop preterm PE. Urinary soluble endoglin has only limited ability to determine the severity of PE and to distinguish between PE and chronic hypertension both preterm and at term. Compared with urinary soluble endoglin, the soluble fms-like tyrosine kinase 1 to PlGF ratio remains a better marker of disease presence, severity and outcome.