2011 · 20 citations · 0 references
MedicineGeneticsMolecular GeneticsHuman GeneticsIntracellular TransportAirway DiseasesChloride Channel BiophysicsChloride HomeostasisCystic FibrosisFibrosisMembrane TransportAutosomal Recessive InheritanceCftr Gene MutationsChloride Channel DisordersChloride Channel DysfunctionChloride TransportChloride Transport DefectsEpithelial Chloride SecretionInherited Chloride Transport Disorders
Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator ...