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IGF-1 and IGF-1BP3 in gastric adenocarcinoma. Preliminary study.

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References

2003

Year

Claudio Franciosi, Maria Gaia Piacentini, Matteo Conti, Fabrizio Romano, F Musco, Roberto Caprotti, Franco Rovelli, Franco Uggeri
PubMed

Abstract

IGF-1 values in gastric cancer patients are increased compared to control group, without stratification for stage and nodal status. Moreover radical surgery, with complete tumor ablation, induces a significant decrease in IGF-1 levels, without reach normal limits. Besides at baseline abnormally higher IGF-1BP3 values were observed, suggesting an alteration in IGF-1 and IGF-1BP3 system.