Screening of Caesalpinia pulcherrima Linn Flowers for Analgesic and Anti-inflammatory Activities

Abstract

Summary: The flowers of Caesalpinia pulcherrima were extracted with methanol to determine their analgesic and anti-inflammatory activities. Intraperitoneal administration of methanolic extract (75, 150 and 225 mg/kg) produced significant analgesic activity in acetic acid-induced writhing, tail immersion test and hot plate tests and anti-inflammatory effect against carrageenan-induced paw edema in experimental animals. Industrial relevance: The herbal medicines are getting more importance in the treatment of inflammation because of the side effect of the current therapy used to treat those inflammation using synthetic drugs. Herbal medicines have less side effects and less costly when compared to the synthetic drugs. The present study will help the industry to produce herbal drug with less side effect, less costly affordable and more effective in the treatment of pain and inflammation. Finally the phytochemical screening or elucidation of the bioactive compounds from the plant would be effective drug against pain and inflammation.