Concepedia

Debate: The slippery slope of surrogate outcomes

Ralph B. D’Agostino

Trials · 2000 · 45 citations · 11 references

DOIFull text

Open access

Concepts

References

11

Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women

Stephen B. Hulley · JAMA · 1998 · 6.3K citations

, , +17

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

Jan A. Staessen, Robert Fagard, Lutgarde Thijs et al. · The Lancet · 1997 · 3K citations

, , +9

Major Cardiovascular Events in Hypertensive Patients Randomized to Doxazosin vs Chlorthalidone: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group · JAMA · 2000 · 1.5K citations

, , +16

Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group

John B. Kostis · JAMA · 1997 · 535 citations

, , +12

Prevention of Heart Failure by Antihypertensive Drug Treatment in Older Persons With Isolated Systolic Hypertension

John B. Kostis · JAMA · 1997 · 494 citations

, , +17