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A novel Cu(OTf)2 mediated three component high yield synthesis of α -aminophosphonates
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2006
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High YieldsInorganic ChemistryChemical EngineeringRoom TemperatureEngineeringCatalytic SynthesisNovel CuOrganic ChemistryOrganometallic CatalysisCatalysisChemistryCorresponding αAminophosphonatesα -AminophosphonatesSynthesis MethodSynthetic ChemistryBiomolecular Engineering
Copper(II) triflate catalyzes efficiently the three-component condensation reaction of an aldehyde, amine and P(OMe) 3 in acetonitrile at room temperature to afford the corresponding αaminophosphonates in high yields.