PubMed · 2000 · 10 citations · 1 references
MedicineInfectious DiseasesPediatricsNeonatologyPediatric Infectious DiseasesPreterm BirthCare Of Premature InfantsInfant Infectious DiseasesNeonatal InfectionsNeonatal Infectious DiseasesNeonatal Respiratory DisordersRespiratory DiseaseAntiviral Therapy In NeonatesGestation PeriodInfection Risk FactorsNeonatal Antiviral TherapyNeonatal Chronic Lung DiseaseNeonatal RiskPrematurity-related Respiratory MorbidityRespiratory Syncytial Virus Prophylaxis
Premature babies < = 35 weeks gestation, with or without chronic lung disease (CLD), should be considered high risk population for RSV infection and rehospitalization. RSV monoclonal antibodies (palivizumab) have been found useful in decreasing rates of RSV hospitalization in this patients. Guidelines for their administration include: 1. Recommend their use in premature born between 29-32 weeks gestation without CLD and less than 6 months at entry of RSV station. 2. Strongly recommend their use in premature babies < = 28 weeks gestation or affected with CLD in treatment during last 6 months. These patients should be prophylaxed for two RSV seasons. 3. Prophylaxis among premature babies between 32-35 weeks gestation is not recommended on routine bases. Each case has to be individually analyzed considering risk factors.
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Syd Johnson, Cynthia N. Oliver, Gregory A. Prince et al. · The Journal of Infectious Diseases · 1997 · 641 citations · Full text