Efficacy of Febuxostat for Slowing the GFR Decline in Patients With CKD and Asymptomatic Hyperuricemia: A 6-Month, Double-Blind, Randomized, Placebo-Controlled Trial

A Role for Uric Acid in the Progression of Renal Disease

Duk‐Hee Kang, Takahiko Nakagawa, Lili Feng et al. · Journal of the American Society of Nephrology · 2002 · 1.3K citations

Medicine, Nephrology, Surgery +8

Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism

Marilda Mazzali, Jeremy Hughes, Yoon-Goo Kim et al. · Hypertension · 2001 · 1.3K citations

Medicine, Nephrology, Pharmacology +10

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

Marián Goicoechea, Soledad García de Vinuesa, Úrsula Verdalles et al. · Clinical Journal of the American Society of Nephrology · 2010 · 829 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats

Laura Gabriela Sánchez‐Lozada, Edilia Tapia, José Santamaría et al. · Kidney International · 2004 · 558 citations

Medicine, Nephrology, Physiology +16

Uric Acid and Long-term Outcomes in CKD

Magdalena Madero, Mark J. Sarnak, Xuelei Wang et al. · American Journal of Kidney Diseases · 2009 · 435 citations · Full text

Medicine, Biochemistry, Nephrology +11