Complexes between nucleic acid bases and bivalent metal ions. IV. Syntheses and spectroscopic analyses of adenine-zinc chloride and -calcium chloride complexes.

Abstract

New 1 : 1 adenine-ZnCl2 and 2 : 1 adenine-CaCl2 complexes were obtained from water, ethanol, or 90% ethanol solution. The infrared and proton magnetic resonance spectra of the complexes were characterized to investigate the binding site of the metal to adenine by comparison with those of other adenine-metal complexes. On the basis of these data, it is suggested that Zn or Ca is coordinated with the N (1) site of neutral adenine base.