9‐Phenanthrol inhibits recombinant and arterial myocyte <scp>TMEM</scp>16<scp>A</scp> channels

Abstract

These data identify 9-phenanthrol as a novel TMEM16A channel blocker and provide an explanation for the previous observation that 9-phenanthrol abolishes myogenic tone when both TRPM4 and TMEM16A channels contribute to this response. 9-Phenanthrol may be a promising candidate from which to develop TMEM16A channel-specific inhibitors.