Reduced drug elimination in congestive heart failure

A physiological approach to hepatic drug clearance

G. Wilkinson, David G. Shand · Clinical Pharmacology & Therapeutics · 1975 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

THE FATE OF AMINOPYRINE (PYRAMIDON) IN MAN AND METHODS FOR THE ESTIMATION OF AMINOPYRINE AND ITS METABOLITES IN BIOLOGICAL MATERIAL

Bernard B. Brodie, Julius Axelrod · Journal of Pharmacology and Experimental Therapeutics · 1950 · 305 citations

Medicine, Pharmacokinetics, Pharmacology +8

Interrelationships of Hepatic Blood Flow, Cardiac Output, and Blood Levels of Lidocaine in Man

Robert E. Stenson, Robert T. Constantino, Donald C. Harrison · Circulation · 1971 · 271 citations · Full text

Medicine, Pharmacology, Physiology +17

Quantitative Assessment of Hepatic Function by Breath Analysis after Oral Administration of [¹⁴C]aminopyrine

Gershon W. Hepner · Annals of Internal Medicine · 1975 · 207 citations

Medicine, Pharmacokinetics, Pharmacology +14

Assessment of Aminopyrine Metabolism in Man by Breath Analysis after Oral Administration of¹⁴C-Aminopyrine

Gershon W. Hepner, Elliot S. Vesell · New England Journal of Medicine · 1974 · 197 citations

Pharmacy, Pharmacology, Drug Clearance +9