A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants

<i>daf-2</i> , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in <i>Caenorhabditis elegans</i>

Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu et al. · Science · 1997 · 2.3K citations

Life Sciences, Biology, Genetics +17

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

Scott Ogg, Suzanne Paradis, S Gottlieb et al. · Nature · 1997 · 2K citations

Life Sciences, Genetics, Molecular Biology +13

<i>daf-16</i> : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of <i>Caenorhabditis elegans</i>

Kui Lin, Jennie B. Dorman, Aylin R. Rodan et al. · Science · 1997 · 1.5K citations

Life Sciences, Biology, Genetics +12

Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in <i>Drosophila melanogaster</i>

William C. Orr, Rajindar S. Sohal · Science · 1994 · 1.5K citations

Life Sciences, Entomology, Genetics +17

A conserved tripeptide sorts proteins to peroxisomes.

Stephen J. Gould, G A Keller, Nancy Hosken et al. · The Journal of Cell Biology · 1989 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17