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MedicineCardiologyPharmacotherapyClinical MedicineClinical PharmacologyEvidence-based PracticeBlood Pressure ControlBlood Pressure ManagementClinical Trial DesignClinical TrialsHypertension ControlRandomized Controlled TrialsAntihypertensive Drug TherapyAntihypertensive TreatmentTreatment-resistant Hypertension