The safety and adequacy of resection on hepatocellular carcinoma larger than 10 cm: A retrospective study over 10 years

Abstract

Tumor-free margin is an independent risk factor for recurrence but has no impact on OS. Surgical margin >1 mm is adequate in patients with tumors ≥10 cm. Postoperative close follow up, especially of distant metastasis, and appropriate treatment of recurrence by a multidisciplinary approach may improve prognosis.