Protein-carbohydrate interaction. XIX. The interaction of concanavalin A with IgM and the glycoprotein phytohemagglutinins of the waxbean and the soybean.

Abstract

The specific interaction of concanavalin A, the phytohemagglutinin of the jack bean ( Canavalia ensiformis ), with several glycoproteins has been studied. It is demonstrated that concanavalin A forms precipitates with purified monoclonal IgM and the glycoprotein phytohemagglutinins (lectins) from waxbean and soybean. It is suggested that the carbohydrate residues reactive with concanavalin A are situated on the surface of these glycoproteins.