HYPERCHOLESTEREMIA: AN ANALYSIS OF 529 CASES AND TREATMENT OF 297 BY A LOW ANIMAL FAT DIET AND DESICCATED THYROID SUBSTANCE

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Article1 October 1951HYPERCHOLESTEREMIA: AN ANALYSIS OF 529 CASES AND TREATMENT OF 297 BY A LOW ANIMAL FAT DIET AND DESICCATED THYROID SUBSTANCEW. W. PRIDDLE, M.D., F.A.C.P.W. W. PRIDDLE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-4-836 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEvidence is gradually accumulating that the genesis of human atherosclerosis is somehow associated with cholesterol metabolism. Myxedema, poorly-controlled diabetes, xanthomatosis and nephrosis have in common a high serum cholesterol, and they are prone to develop premature and severe grades of atherosclerosis.Anitschkow1in 1912, by feeding rabbits pure cholesterol dissolved in a vegetable oil, was successful in producing experimental atherosclerosis. In 1933 he expressed the opinion, in reviewing the literature up to that time, that the experimental lesions in rabbits were the same as those of human atherosclerosis. Duff2stated in 1935, in an extensive review, that there was insufficient...Bibliography1. Anitschkow N: Experimental arteriosclerosis in animals, Chapter X in: Cowdry, E. V.: Arteriosclerosis, a survey of the problem, 1933, the Macmillan Company, New York, p. 271. Google Scholar2. Duff GL: Experimental cholesterol arteriosclerosis and its relationship to human arteriosclerosis, Arch. Path. 20: 81, 259, 1935. Google Scholar3. Leary T: Atherosclerosis, the important form of arteriosclerosis, a metabolic disease, J. A. M. A. 105: 475, 1935. CrossrefGoogle Scholar4. Leary T: Atherosclerosis. Etiology, Arch. Path. 21: 459, 1936. Google Scholar5. SteinerKendall AFE: Atherosclerosis and arteriosclerosis in dogs following ingestion of cholesterol and thiouracil, Arch. Path. 42: 433, 1946. Google Scholar6. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPotassium in hypertensionDer Einfluß eines an essentiellen Fettsäuren reichen Triglyceridgemisches auf die Cholesteringehalte von Blut, Leber und Gehirn der RattePharmacology of Drugs Used in the Control of HypercholesterolemiaDie Grundstoffe der NahrungKrankheiten der GefäßeDie Pathogenese der Arteriosklerose als StoffwechselproblemErnährungskrankheitenErnährungskrankheitenLipoidstoffwechsel und ArterioskleroseHypercholesteremia: Its Clinical Significance and Management 1 October 1951Volume 35, Issue 4Page: 836-847KeywordsAtherosclerosisCholesterolDietFatsHypercholesterolemiaLesionsOilsRabbitsThyroid ePublished: 1 December 2008 Issue Published: 1 October 1951 PDF downloadLoading ...