Increased CD4⁺CD69⁺CD25^‐ T cells in patients with hepatocellular carcinoma are associated with tumor progression

Abstract

Increased CD4(+) CD69(+) CD25(-) T cells in HCC patients are significantly correlated with tumor size, vascular invasion and TNM stage. Thus, increased CD4(+) CD69(+) CD25(-) T cells exert a critical role in HCC progression and might be a clinically aggressive phenotype of HCC.