PubMed · 1965 · 82 citations · 0 references
Life SciencesImmunologyAdaptive ImmunityHypersensitivityMonoclonal AntibodiesAntibody CharacterizationImmunoglobulin FunctionAgglutination ReactionsAntibodiesAntigen-antibody Complex FormationCombining Ability EffectsCombining Ability Testing
A class of 7 S lysins and agglutinins, of γ1 and γ2 mobilities, was found to be sensitive to ME. Such antibodies were encountered during the early phases of the 7 S antibody formation in primary and secondary responses. In contrast to 19 S antibodies, which lost all serologic activity after ME treatment, these sensitive 7 S antibodies fully maintained their combining ability.