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STUDIES ON MOUSE ANTIBODIES. I. THE RESPONSE TO SHEEP RED CELLS.
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1965
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ImmunohematologyCaprineLaboratory ImmunologyImmunodeficienciesImmunologyImmunodominanceEducationImmune SystemImmunotherapyγ2 MobilitiesSerologic TestingImmunochemistryAutoantibodiesS LysinsAnimal PhysiologyAllergyAutoimmunityHumoral ImmunityImmune FunctionAntibody ScreeningSensitive 7Autoantibody ProductionAnimal ScienceVeterinary ScienceImmunoglobulin EMedicineLysosomal Storage Disease
A class of 7 S lysins and agglutinins, of γ1 and γ2 mobilities, was found to be sensitive to ME. Such antibodies were encountered during the early phases of the 7 S antibody formation in primary and secondary responses. In contrast to 19 S antibodies, which lost all serologic activity after ME treatment, these sensitive 7 S antibodies fully maintained their combining ability.