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A <i>SALMONELLA NEWPORT</i> OUTBREAK IN A PREMATURE NURSERY WITH A ONE-YEAR FOLLOW-UP
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1966
Year
Incubation PeriodGastroenterologyBacterial PathogensTraveler DiarrheaPremature InfantsPathogen TransmissionInfection ControlAntimicrobial ResistanceInfectious Disease EpidemiologyClinical MicrobiologyEpidemiologyMicrobial DiseaseAntibioticsTyphoid FeverFoodborne IllnessPathogenesisPediatricsParenteral Penicillin GPediatric GastroenterologyGastrointestinal PathologyMicrobiologyMedicine
Gastroenteritis due to S. newport occurred in 11 premature infants. Meningitis due to this organism developed in a twelfth infant after an incubation period of 1 month. Oral ampicillin (following parenteral penicillin G and kanamycin) was clinically effective as specific therapy in all 11 cases of gastroenteritis, but there was a recurrence of the organism in the stools of 9 of 11 infants during or after ampicillin therapy. No toxicity with ampicillin was found. At 2 months after the start of the disease 6 of 11 infants had positive stool cultures. Of the 10 followed for 1 year, 4 had positive cultures at 8 months and 1 at 12 months.