Studies on heterocyclic ketenethioacetal derivatives. VII. Reactions of 3-ethyl-5-bis(methylthio)methylene-2-thioxothiazol-4(5H)-one.

Abstract

3-Ethyl-5-bis (methylthio) methylene-2-thioxothiazol-4 (5H) one (2), which was prepared by the reaction of 3-ethylrhodanine with carbon disulfide in the presence of sodium hydroxide in dimethyl sulfoxide, reacted with nucleophilic reagents such as amines or active methylenes to give the corresponding replacement products of one or two methylthio groups in good yield.