A randomized controlled clinical trial: Interruption of intrauterine transmission of hepatitis B virus infection with HBIG

Abstract

It is effective and safe to prevent intrauterine infection of HBV with HBIG from the 28(th) wk in pregnant women with positive HBeAg and HBsAg. In clinical application, those pregnant women with negative HBeAg and positive HBV-DNA also need to be interrupted by HBIG.