PubMed · 2000 · 79 citations · 0 references
Life SciencesMicrobiologyPharmacologyAntimicrobial ResistanceBacteriologyMedical MicrobiologyAntibacterial ResistanceAntibiotic ResistanceAntibiotic Resistance MechanismsAntimicrobial Drug InteractionsCombination Antimicrobial TherapyMultidrug ResistanceAntibacterial PropertiesMinimum Inhibitory Concentration DeterminationMulti-drug ResistanceMultidrug-resistant OrganismsMultidrug-resistant PathogensPseudomonas Aeruginosa ResistancePseudomonas SpeciesTreatment Of Bacterial Resistance
A total of 15 bacterial strains (7 Pseudomonas & 8 Klebsiella species) isolated from various samples which showed multi-drug resistance were studied to verify in vitro antibacterial action of honey on the principle of Minimum Inhibitory Concentration (MIC) & its synergism with 3 common antibiotics--Gentamicin, Amikacin & Ceftazidime. The MIC of honey with saline for both organisms was found to be 1:2. The synergistic action was seen in the case of Pseudomonas spp. and not with Klebsiella spp.