FEBS Letters · 1983 · 282 citations · 19 references
Life SciencesBiochemistryChemistryRedox BiochemistryAntioxidant DefenseOxidation ReactionsOxidative Damage To BiomoleculesOxidative StressRadical ReactionsReactive Oxygen SpeciesFenton ReactionFree Radical OxidationFree Radical ScavengingHydroxyl Radical ChemistryHydroxyl Radical GenerationInorganic SaltsRadical Production Pathways
In the presence of physiological concentrations of iron(III) salts, superoxide radical and hydrogen peroxide can interact to form the highly‐damaging hydroxyl radical. No specific added ‘chelator’ of iron salts is necessary for this reaction to occur.
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