Free amino acids in normal and neoplastic tissues of mice as studied by paper chromatography.

Abstract

Summary Patterns of free amino acids determined by two-dimensional paper chromatography were studied in a variety of mouse tumors, comparing the neoplasms in several cases with the normal homologous tissues. It was found that each normal tissue examined had a distribution of free amino acids characteristic for that tissue, while all of the tumors, regardless of derivation or source, showed very similar patterns.