Changes of bladder activity and glycine levels in the lumbosacral cord after partial bladder outlet obstruction in rats

Abstract

Detrusor overactivity during the chronic phase of partial BOO is partly caused by a decrease of glycinergic neuronal activity in the lumbosacral cord. A 3-day period of BOO produces detrusor overactivity, which might be due to an irreversible decrease of spinal glycinergic neuronal activity.