Organotin(IV) Carboxylates of Substituted<i>α</i>‐Cinnamic Acid, R<i>_n</i>Sn(OCOC(R²)=CHR¹)_{4 –}<i>_n</i>: Synthesis, Spectroscopic Characterization and Biological Evaluation

Abstract

ABSTRACT Di‐ and triorganotin(IV) carboxylates, R n Sn(OCOC(R 2 )=CHR 1 ) 4–n ( n = 2 and 3; R = Me, Et, n ‐Bu, Ph; R 1 = 3‐CH 3 O‐4‐OHC 6 H 3 , R 2 = C 6 H 5 ) were prepared by reacting the corresponding organotin(IV) chloride with the silver salt of the ( E )‐3‐(4‐hydroxy‐3‐methoxyphenyl)‐2‐phenylpropenoic acid. The title compounds were investigated and characterized by elemental analysis, infrared (FT‐IR), multinuclear ( 1 H, 13 C, 119 Sn) NMR, and mass spectrometry, and possible structures were proposed. The complexes and ligand acid ( HL ) have been evaluated in vitro against various bacteria and fungi. The results noticed during the biocidal activity screenings proved their in vitro biological potential. They were also tested for cytotoxicity.