Comparative In Vitro Study of Different Atmospheric Pressure Plasma Jets Concerning their Antimicrobial Potential and Cellular Reaction

Abstract

Atmospheric pressure plasma‐jets could be an alternative method to remove bacterial biofilms on orthopaedic implants. Furthermore, plasma‐exposure might support the proliferation of osteoblasts after cleaning implants by activating the implant surface. In this comparative in vitro study, the efficacy of five different plasma sources concerning removal of bacterial biofilms and influence on human osteoblast cell attachment was tested. Two plasma sources revealed a significant reduction of bacterial viability (>90%) and enhanced spreading of osteoblastic cells. Promising results and potential for local plasma‐jet application dealing with implant‐related infections caused by bacterial biofilms was demonstrated.