Subcutaneous Fat Necrosis with Extensive Calcification After Hypothermia in Two Newborn Infants

Abstract

In two infants who had been immersed in ice water as treatment for neonatal asphyxia, subcutaneous fat necrosis and severe calcification without hypercalcemia appeared 2 to 5 weeks after the procedure. Growth and development have been normal. This complication must be taken into account in assessing the value of hypothermia as treatment for neonatal asphyxia.