Clinical Science · 1980 · 55 citations · 0 references
MedicineBiochemistryEndocrinologyBone MetabolismMineral MetabolismWomen's HealthBone HealthBone Metabolism DisordersMetabolic Bone DiseaseOsteoporosisBone Enzyme MarkersBone Mineral LossHydroxyproline ContentMenopausal Bone LossOsteoporosis In WomenPhosphatase Enzyme ActivityPostmenopausal Bone ResorptionPostmenopausal Changes
1. Plasma alkaline phosphatase activity and urine hydroxyproline excretion were measured in age-matched premenopausal and postmenopausal women. 2. Both measurements were found to be significantly higher in postmenopausal women. 3. It is proposed that the rise in the plasma alkaline phosphatase, like that in the hydroxyproline excretion, may reflect the onset of bone loss that occurs after the menopause.