Ischemic Preconditioning Attenuates Postischemic Leukocyte - Endothelial Cell Interactions Role of Nitric Oxide and Protein Kinase C

Abstract

Both NOS and PKC play a protective role during IPC, but probably in distinct ways. Furthermore, the results also indicate that eNOS, but not nNOS nor iNOS, is the key mediator of IPC-attenuated I/R-induced microcirculatory disturbance.