The molecular basis of alpha-thalassaemia in Thailand.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

Joyce Lauer, Che‐Kun James Shen, Tom Maniatis · Cell · 1980 · 531 citations

Sequence Homology, Cytogenetics, Chromosomal Arrangement +9

α-Thalassaemia caused by a polyadenylation signal mutation

Douglas R. Higgs, S. E. Y. Goodbourn, Janette Lamb et al. · Nature · 1983 · 406 citations

Polyadenylation Signal Mutation, Genetic Disorder, Medicine +5

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

Stylianos E. Antonarakis, Corinne D. Boehm, Patricia J. Giardina et al. · Proceedings of the National Academy of Sciences · 1982 · 402 citations · Full text

Genetics, Genetic Epidemiology, Human Polymorphism +26

Insertion of synthetic copies of human globin genes into bacterial plasmids

John T. Wilson, Lois B. Wilson, Jon K. deRiel et al. · Nucleic Acids Research · 1978 · 346 citations · Full text