The Journal of Urology · 1984 · 160 citations · 10 references
MedicineOncologyUrologyCancer ScreeningGenitourinary OncologyProstate DiseaseMalignant NeoplasmsProstate CancerProstate PathologyProstatic PathologyUrologic Cancer DiagnosisProstate AdenocarcinomaProstate Cancer DiagnosisProstatic AdenocarcinomaRoutine Screening
The results of routine urological screening of 2,005 men between 40 and 70 years old were reviewed. Digital rectal examination was used to screen for adenocarcinoma of the prostate. Of 65 nodules detected 17 proved to be adenocarcinoma. Clinical staging revealed no evidence of metastases in all but 2 patients but pathological (surgical) examination resulted in upstaging of disease in 66 per cent of the patients who underwent an operation. Digital rectal examination proved to be an insensitive screening device with poor predictive value. The use of adjunctive screening tools for detection of adenocarcinoma of the prostate is suggested.
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Origin and development of carcinoma in the prostate
John E. McNeal · Cancer · 1969 · 396 citations · Full text
The Accuracy of the Rectal Examination in the Diagnosis of Prostate Carcinoma
Patrick Guinan, Irving M. Bush, V. Ray et al. · New England Journal of Medicine · 1980 · 125 citations