Increased Muscle Activity During Rapid Eye Movement Sleep Correlates with Decrease of Striatal Presynaptic Dopamine Transporters. IPT and IBZM SPECT Imaging in Subclinical and Clinically Manifest Idiopathic REM Sleep Behavior Disorder, Parkinson's Disease, and Controls

Abstract

This study suggests that there is a continuum of reduced striatal dopamine transporters involved in the pathophysiologic mechanisms causing increased muscle activity during REM sleep in patients with subclinical RBD.