Modafinil for the Treatment of Daytime Sleepiness in Parkinson´s Disease: A Double-blind, Randomized, Crossover, Placebo-controlled Polygraphic Trial

Abstract

The results of this study suggest that modafinil improves daytime sleepiness in PD patients, at least on a subjective or behavioral level. Modafinil treatment may be considered for EDS in PD patients, in whom otherwise treatable causes of Excessive Daytime Sleepiness (EDS) are absent.