Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor.

Tao Zhu, Wei Zhang, Daoxin Wang, Niwen Huang, Bo Hong, Wang Deng, Jia Deng

PubMed · 2012 · 35 citations · 0 references

Abstract

Based on its ability to reduce the inflammatory response and mucus hypersecretion by regulating GABAAR activity in a murine model of chronic asthma, rosuvastatin may be a useful therapeutic agent for treatment of asthma.