PubMed · 2013 · 13 citations · 0 references
Life SciencesEmergency MedicinePharmacologyAllergyHypersensitivityPediatric AllergyAllergic ConditionsAllergy PreventionAnaphylaxisDrug AllergyEmergency PharmacologyVenom AllergyAdrenaline TreatmentAnaphylaxis Action PlansAnaphylaxis Emergency ManagementAnaphylaxis In ChildrenAnaphylaxis Recognition And TreatmentAnaphylaxis TreatmentAnaphylaxis TriggersEmergency Action Plan Maintenance
OBJECTIVE: This article summarises current knowledge regarding the identification, management and prevention of anaphylaxis, highlighting risk minimisation strategies relevant to general practitioners. DISCUSSION: The most common causes of anaphylaxis are medication, food and insect venom. Medications are the most common cause of anaphylaxis in older adults, particularly antibiotics, anaesthetic drugs, nonsteroidal anti-inflammatory drugs and opiates. Food allergy is the most common cause of anaphylaxis in children, but rarely results in death. Anaphylaxis is a medical emergency requiring immediate treatment with adrenaline, as well as ongoing management. Important steps for long-term risk minimisation include avoidance of triggers, prescription of an adrenaline autoinjector, maintenance of a personalised emergency action plan for anaphylaxis, education for patients and families and regular review to optimise management.