The effects of external CO2 application on human skin microcirculation investigated by laser Doppler flowmetry.

Abstract

The effects of an aqueous solution of CO2 applied to a small skin site were investigated by means of a laser Doppler flowmeter. The circulatory response to CO2 was an increased blood flow, reaching a maximum level within approximately 2-3 minutes. In addition there was a marked stimulation of rhythmical vasomotion, especially an increase in amplitudes. The effects, strongly dependent on dose and temperature, ceased rapidly when the CO2 sample was withdrawn.